15 années d'expertise indépendante sur les organismes génétiquement modifiés et leur impact sanitaire.

News from China !!

Wednesday 10 June 2015

China's Ministry of Agriculture has decided not to renew biosafety certificates that allowed research groups to grow genetically modified (GM) rice and corn. The permits, to grow two varieties of GM rice and one transgenic corn strain, expired on 17 August. The reasoning behind the move is not clear, and it has raised questions about the future of related research in China.

Letter to the Editor regarding ‘‘Delaney et al., 2014’’: Uncontrolled GMOs and their associated pesticides make the conclusions unreliable

Tuesday 1 July 2014

/user/image/ogmPicture_335122.pngFood and Chemical Toxicology, july 2014

DOI: 10.1016/j.fct.2014.07.003


Robin Mesnage ; Nicolas Defarge ; Joël Spiroux de Vendômois ; Gilles-Eric Séralini

Conflicts of interests, confidentiality and censorship in health risk assessment: the example of an herbicide and a GMO

Tuesday 24 June 2014

Environmental Sciences Europe 2014, 26:13
Open Access

Gilles-Eric Séralini , Robin Mesnage, Nicolas Defarge and Joël Spiroux de Vendômois


The present opinion is a summary of the debate resulting in this retraction, as it is a historic example of conflicts of interest in the scientific assessments of products commercialized worldwide. We also show that the decision to retract cannot be rationalized on any discernible scientific or ethical grounds. Censorship of research into health risks undermines the value and the credibility of science; thus, we republish our paper.

Republished study: long-term toxicity of a Roundup herbicide and a Roundup-tolerant genetically modified maize

Tuesday 24 June 2014

/user/image/ogmPicture_456434.pngEnvironmental Sciences Europe 2014, 26:14  doi:10.1186/s12302-014-0014-5


Gilles-Eric Séralini1, Emilie Clair, Robin Mesnage, Steeve Gress, Nicolas Defarge, Manuela Malatesta, Didier Hennequin and Joël Spiroux de Vendômois


Conclusion : Our findings imply that long-term (2 year) feeding trials need to be conducted to thoroughly evaluate the safety of GM foods and pesticides in their full commercial formulations.

The Need for a Closer Look at Pesticide Toxicity during GMO Assessment

Thursday 1 May 2014

/user/image/ogmPicture_997537.pngPractical Food Safety: Contemporary Issues and Future Directions, First Edition. 632 pages

ISBN: 978-1-118-47460-0
Robin Mesnage and Gilles-Éric Séralini
University of Caen, CRIIGEN and Pole Risk MRSH-CNRS, Caen Cedex, France

Public policy is regularly shaken by health crises or unexpected discoveries; future directions in toxicology assessment are therefore urgently needed. This chapter focuses on agricultural genetically modified organisms (GMOs) because they are essentially pesticide-plants, designed to tolerate and/or produce new pesticide residues in food and feed.

Human cell toxicity of pesticides associated to wide scale agricultural GMOs

Thursday 10 January 2013

Implications of GM-Crop Cultivation at Large Spatial Scales.

Breckling, B. & Verhoeven, R. (2012)

Theorie in der Ökologie 16. Frankfurt, Peter Lang.

Robin Mesnage, Steeve Gress, Nicolas Defarge & Gilles-Eric Séralini
(University of Caen, Institute of Biology, CRIIGEN and Risk Pole, MRSH-CNRS, Caen
Cedex, France)

Comment in Nature : Health effects of pesticides are overlooked in GMO risk assessments

Thursday 15 November 2012

Comment #57505 in Nature on 491, 327 (2012)


G.E. Séralini, R. Mesnage, N. Defarge.
University of Caen, Institute of Biology, CRIIGEN and Risk Pole, MRSH-CNRS, EA 2608, Esplanade de la Paix, Caen Cedex 14032, France

Transgenic aubergines put on ice

Monday 19 October 2009

Published online 19 October 2009 | Nature | doi:10.1038/4611041a


Transgenic aubergines put on ice - original article by K.S. Jayaraman

Comment by Gilles-Eric Séralini, Prof. University of Caen and CRIIGEN, ENSSER, France, 17 Nov, 2009 in naturenews

Conclusiveness of toxicity data and double standards

Friday 18 April 2014

Food and Chemical Toxicology


Comment on your answers (Hayes, 2014a) concerning the retraction of our study (Seralini et al., 2012 and Hayes, 2014b) by Food and Chemical Toxicology (FCT)

Answers to critics: Why there is a long term toxicity due to a Roundup-tolerant genetically modified maize and to a Roundup herbicide.

Sunday 17 March 2013

Food Chem Toxicol. 2013 Mar;53:476-83. doi: 10.1016/j.fct.2012.11.007. Epub 2012 Nov 9.


Séralini GE, Mesnage R, Defarge N, Gress S, Hennequin D, Clair E, Malatesta M, de Vendômois JS.

Les OGM agricoles aujourd’hui Que sont-ils et participent-ils à la faim dans le monde ?

Friday 1 March 2013

Christian Vélot et Gilles-Éric Séralini

Depuis leur origine en 1994, les organismes génétiquement modifiés (OGM) agricoles commercialisés, cultivés en plein champ, sont le centre d’in-
térêts puissants et controversés : ils ont permis d’accroître considérablement les brevets sur les semences vivantes. Cela est unique dans l’histoire du commerce alimentaire. Par ailleurs, leurs évaluations sanitaires sont un sujet brûlant où les débats internationaux font rage, ce qui met en cause leur rentabilité. Ils sont pourtant présentés comme le moyen de combattre la faim dans le monde : qu’en est-il exactement ?

Long term toxicity of a Roundup herbicide and a Roundup-tolerant genetically modified maize

Tuesday 18 September 2012

Food and Chemical Toxicology
Volume 50, Issue 11, November 2012, Pages 4221–4231
DOI: 10.1016/j.fct.2012.08.005


Gilles-Eric Séralini , Emilie Clair , Robin Mesnage, Steeve Gress, Nicolas Defarge, Manuela Malatesta, Didier Hennequin , Joël Spiroux de Vendômois


The health effects of a Roundup-tolerant genetically modified maize (from 11% in the diet), cultivated with or without Roundup, and Roundup alone (from 0.1 ppb in water), were studied 2 years in rats. In females, all treated groups died 2–3 times more than controls, and more rapidly.

A framework for a European network for a systematic environmental impact assessment of genetically modified organisms (GMO)

Tuesday 17 January 2012

BioRisk 01/2012; 7:73-97. DOI:10.3897/biorisk.7.1969


Frieder Graef 1, 22 , Jörg Römbke 2 , Rosa Binimelis 3 , Anne Ingeborg Myhr 4 , Angelika Hilbeck 5 , Broder Breckling 6 , Tommy Dalgaard 7 , Ulrich Stachow 1 , Georgina Catacora-Vargas 4 , Thomas Bøhn 4, 28 , David Quist 4 , Béla Darvas 8, 29 , Gert Dudel 9 , Bernadette Oehen 10 , Hartmut Meyer 11 , Klaus Henle 12 , Brian Wynne 13 , Marc J. Metzger 14 , Silvio Knäbe 15 , Josef Settele 16 ,András Székács 8, 29 , Angelika Wurbs 1 , Jeannette Bernard 17 , Donal Murphy-Bokern 18 , Marcello Buiatti 19 , Manuela Giovannetti 19 , Marko Debeljak 20 , Erling Andersen 21 , Andreas Paetz 17 , Saso Dzeroski 20 , Beatrix Tappeser 22 , Cornelis A.M. van Gestel 23 , Werner Wosniok 24 , Gilles-Eric Séralini 25 , Iulie Aslaksen 26, 4 , Roland Pesch 6 , Stanislav Maly 27 ,
Armin Werner 1

Genetically modified crops safety assessments: present limits and possible improvements

Tuesday 1 March 2011

Gilles-Eric Séralini, Robin Mesnage, Emilie Clair, Steeve Gress, Joël Spiroux de Vendômois, Dominique Cellier, Environmental Sciences Europe 2011, 23:10


The 90-day-long tests are insufficient to evaluate chronic toxicity, and the signs highlighted in the kidneys and livers could be the onset of chronic diseases. However, no minimal length for the tests is yet obligatory for any of the GMOs cultivated on a large scale, and this is socially unacceptable in terms of consumer health protection.

Debate on GMOs Health Risks after Statistical Findings in Regulatory Tests

Tuesday 5 October 2010

International Journal of Biological Sciences

Joël Spiroux de Vendômois 1 , Dominique Cellier 1,2 , Christian Vélot 1,3 , Emilie Clair 1,4 , Robin Mesnage 1,4 , and Gilles-Eric Séralini 1,4


We summarize the major points of international debate on health risk studies for the main commercialized edible GMOs. These GMOs are soy, maize and oilseed rape designed to contain new pesticide residues since they have been modified to be herbicide-tolerant (mostly to Roundup) or to produce mutated Bt toxins.

Genetically modified crop consumption at large scale: Possible negative health impacts due to holes in assessment. Overview of the safety studies of GMOs performed on mammals

Tuesday 1 June 2010

Breckling, B. & Verhoeven, R. (2010) Implications of GM-Crop Cultivation at Large Spatial Scales. Theorie in der Ökologie 16. Frankfurt, Peter Lang.


Gilles-Eric Séralini, Joël Spiroux de Vendomois, Dominique Cellier, Robin Mesnage  & Emilie Clair


Recently, a debate on international regulation is ongoing on the capacity to predict and avoid adverse effects on health and environment of new products and novel food/feed (GMOs, chemicals, pesticides, nanoparticles ...). The health risks assessment cannot avoid the study of blood analyses of mammals eating these products in subchronic or chronic tests

A Comparison of the Effects of Three GM Corn Varieties on Mammalian Health

Thursday 10 December 2009

International Journal of Biological Sciences

2009; 5(7):706-726


Joël Spiroux de Vendômois, François Roullier, Dominique Cellier and Gilles-Eric Séralini


We present for the first time a comparative analysis of blood and organ system data from trials with rats fed three main commercialized genetically modified (GM) maize (NK 603, MON 810, MON 863), which are present in food and feed in the world. NK 603 has been modified to be tolerant to the broad spectrum herbicide Roundup and thus contains residues of this formulation

How Subchronic and Chronic Health Effects can be Neglected for GMOs, Pesticides or Chemicals

Tuesday 16 June 2009

Gilles-Eric Séralini 1,2   , Joël Spiroux de Vendômois 2 , Dominique Cellier 2,3 , Charles Sultan 2,4 , Marcello Buiatti 2,5 , Lou Gallagher 6 , Michael Antoniou 7 , Krishna R. Dronamraju8


Chronic health effects are increasing in the world such as cancers, hormonal, reproductive, nervous, or immune diseases, even in young people.

Factors to consider before production and commercialization of aquatic genetically modified organisms: the case of transgenic salmon

Friday 28 November 2008

Environmental science & policy 12 (2009) 170–189, Elsevier


Olivier Le Curieux-Belfond a , Louise Vandelac a,b , Joseph Caron b , Gilles-Eric Seralini a,c, *

New Analysis of a Rat Feeding Study with a Genetically Modified Maize Reveals Signs of Hepatorenal Toxicity

Monday 20 November 2006

Arch. Environ. Contam. Toxicol. 52, 596?602 (2007)
DOI: 10.1007/s00244-006-0149-5

Gilles-Eric Sralini, Dominique Cellier, Jol Spiroux de Vendomois

Health risk assessment of genetically modified organisms (GMOs) cultivated for food or feed is under debate throughout the world, and very little data have been published on mid- or long-term toxicological studies with mammals.

Les transferts génétiques horizontaux

Friday 1 September 2006

Dans l'évaluation des risques associés à la dissémination des OGM, les transferts horizontaux jouent un rôle prépondérant, à ne pas négliger.
Jean-Michel Panoff , Christian Velot , Gilles-Éric Séralini


Biofutur 269, septembre 2006